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Article

The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair.

Nucleic acids research - 1 Jul 2009

Rosado Ivan V, Niedzwiedz Wojciech, Alpi Arno F, Patel Ketan J

Abstract excerpt

FANCM, the most highly conserved component of the Fanconi Anaemia (FA) pathway can resolve recombination intermediates and remodel synthetic replication forks. However, it is not known if these activities are relevant to how this conserved protein activates the FA pathway and promotes DNA crosslink repair. Here we use chicken DT40 cells to systematically dissect the function of the helicase and nuclease domains...

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Source

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Identifiers

PMID: 19465393
DOI: 10.1093/nar/gkp365
PMCID: PMC2715236

Genes

FANCM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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