Article
Rapid detection of polymorphisms of the nitric oxide cascade.
Clinical chemistry and laboratory medicine - 1 Apr 2002
Weiss Johanna, Fricker Ruth, Haefeli Walter E
Abstract excerpt
NOS3 (endothelial nitric oxide (NO) synthase) and p22phox (subunit of NAD(P)H oxidase) are two genes whose products are involved in formation and degradation of NO, a ubiquitous signaling molecule largely responsible for the maintenance of normal endothelial function. The G894T polymorphism of NOS3 and the C242T polymorphism of p22phox are reportedly associated with numerous cardiovascular diseases. For each...
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