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Article

The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer☆☆☆

23 May 2009

Abstract excerpt

OBJECTIVE: Emerging evidence suggests that specific sub-populations of cancer cells with stem cell characteristics within the bulk of tumours are implicated in the pathogenesis of heterogeneous malignant tumours. The cells that drive tumour growth have been denoted cancer-initiating cells or cancer stem cells (hereafter CSCs). CSCs have been isolated initially from leukaemias and subsequently from several solid...

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PMID: 19464919
DOI: 10.1016/j.ejcts.2009.03.063

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