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Article

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

15 Nov 1991

Abstract excerpt

Sunlight is a carcinogen to which everyone is exposed. Its UV component is the major epidemiologic risk factor for squamous cell carcinoma of the skin. Of the multiple steps in tumor progression, those that are sunlight-related would be revealed if they contained mutations specific to UV. In a series of New England and Swedish patients, we find that 14/24 (58%) of invasive squamous cell carcinomas of the skin...

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Identifiers

PMID: 1946433
DOI: 10.1073/pnas.88.22.10124

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Source receipt: pubmed, retrieved 7 Sept 2026.

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