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Article

Evaluation of 13q14 status in patients with chronic lymphocytic leukemia using single nucleotide polymorphism-based techniques.

The Journal of molecular diagnostics : JMD - 1 Jul 2009

Hanlon Katy, Ellard Sian, Rudin Claudius E, Thorne Susan, Davies Teresa, Harries Lorna W

Abstract excerpt

Deletions of chromosome 13q14 are common in chronic lymphocytic leukemia and other cancers, demonstrating the importance of this region in tumorigenesis. We report the use of two single-nucleotide polymorphism (SNP)-based techniques to determine 13q loss of heterozygosity (LOH) status in 15 patients with CLL: (i) digital SNP (dSNP), where analysis of heterozygous SNPs detects allelic imbalances, and (ii) DNA...

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Share to Chromosome Aberrations
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Chromosomes, Human, Pair 13

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Loss of Heterozygosity

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Share to Sensitivity and Specificity

Source

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Identifiers

PMID: 19460942
DOI: 10.2353/jmoldx.2009.080167
PMCID: PMC2710705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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