Article
Interleukin-2 -330 and 166 gene polymorphisms in relation to aggressive or chronic periodontitis and the presence of periodontopathic bacteria.
Journal of periodontal research - 1 Oct 2009
Reichert S, Machulla H K G, Klapproth J, Zimmermann U, Reichert Y, Gläser C, Schaller H-G, Schulz S
Abstract excerpt
BACKGROUND AND OBJECTIVE: As a pro-inflammatory cytokine, interleukin-2 mediates the activation, growth and differentiation of T and B lymphocytes and natural killer cells. Promoter polymorphisms of the interleukin-2 gene have been associated with altered interleukin-2 production or identified as prognostic markers for various infectious diseases. Therefore, the aim of this study was to evaluate two polymorphisms...
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