Interleukin-2 -330 and 166 gene polymorphisms in relation to aggressive or chronic periodontitis and the presence of periodontopathic bacteria.

doi:10.1111/j.1600-0765.2008.01173.x

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Article

Interleukin-2 -330 and 166 gene polymorphisms in relation to aggressive or chronic periodontitis and the presence of periodontopathic bacteria.

Journal of periodontal research - 1 Oct 2009

Reichert S, Machulla H K G, Klapproth J, Zimmermann U, Reichert Y, Gläser C, Schaller H-G, Schulz S

Abstract excerpt

BACKGROUND AND OBJECTIVE: As a pro-inflammatory cytokine, interleukin-2 mediates the activation, growth and differentiation of T and B lymphocytes and natural killer cells. Promoter polymorphisms of the interleukin-2 gene have been associated with altered interleukin-2 production or identified as prognostic markers for various infectious diseases. Therefore, the aim of this study was to evaluate two polymorphisms...

Topics

Adult
Aggregatibacter actinomycetemcomitans
Aggressive Periodontitis
Alleles
Bacteroides
Chronic Periodontitis
Female
Gene Frequency
Genotype
Guanine
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-2

Male

Middle Aged

Periodontal Attachment Loss

Periodontal Pocket

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 19453859
DOI: 10.1111/j.1600-0765.2008.01173.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19453859-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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