Article
Non-significant association between - 330 T/G polymorphism in interleukin-2 gene and chronic periodontitis: findings from a meta-analysis.
BMC oral health - 19 Feb 2020
da Silva Felipe Rodolfo Pereira, Galeno Juliana Gomes, Leal Alessandro Luiz Araújo Bentes, Koga Reyce Santos, Batista Nayana Yared, da Conceição Furtado Silvânia, Vasconcelos Daniel Fernando Pereira, Carvalho Marcelo Diniz, Barcellos José Fernando Marques
Abstract excerpt
BACKGROUND: Chronic periodontitis (CP) is an immune-inflammatory disease that promotes tissue damage around the teeth. Among the several inflammatory mediators that orchestrate the periodontitis, there is the interleukin (IL)-2. Genetic variations in IL2 gene may be associated with the risk and s...
Topics
- Alleles
- Chronic Periodontitis
- Genetic Predisposition to Disease
- Humans
- Interleukin-2
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Risk Factors