Article
Interferon-gamma and interleukin-12 gene polymorphisms and their relation to aggressive and chronic periodontitis and key periodontal pathogens.
Journal of periodontology - 1 Aug 2008
Reichert Stefan, Machulla Helmut K G, Klapproth Jana, Zimmermann Uta, Reichert Yvonne, Gläser Christiane, Schaller Hans-Günter, Schulz Susanne
Abstract excerpt
BACKGROUND: The gene polymorphisms interferon-gamma (IFN-gamma) 874 T/A and interleukin (IL)-12 1188 A/C have been associated with the altered production of cytokines. Therefore, they might be indicative of the occurrence of chronic periodontitis (CP) or aggressive periodontitis (AgP) and the pre...
Topics
- Adenine
- Adult
- Age Factors
- Aggregatibacter actinomycetemcomitans
- Alleles
- Bacteria
- Cytosine
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Gingival Hemorrhage
- Humans
- Interferon-gamma
- Interleukin-12