Article
Investigation of an IL-2 polymorphism in patients with different levels of chronic periodontitis.
Journal of clinical periodontology - 1 Jul 2002
Scarel-Caminaga Raquel M, Trevilatto Paula C, Souza Ana P, Brito Rui B, Line Sergio R P
Abstract excerpt
BACKGROUND: Interleukin-2 (IL-2) is a pro-inflammatory cytokine derived from Th1 cells. This cytokine is involved in B-cell activation and stimulates macrophages, natural killer cells, T-cell proliferation and osteoclast activity. IL-2 has been also implicated in the stimulation of osteoclast activity in bone resorption. OBJECTIVE: In this study the relationship between the polymorphism - 330 (T-->G) in the IL-2...
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