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Homocysteine and cognitive impairment in Parkinson's disease: A biochemical, neuroimaging, and genetic study

18 May 2009

Abstract excerpt

The role of the plasma level of homocysteine (Hcy), as a primary outcome, and the effect of silent cerebrovascular lesions and genetic variants related to Hcy metabolism, as secondary outcomes, in the cognitive decline and dementia in Parkinson's disease (PD) were studied. This case-control study focused on 89 PD patients of minimum 10 years of evolution and older than 60 years, who were neuropsychologically...

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PMID: 19452554
DOI: 10.1002/mds.22522

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