Article
Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD.
Neurology - 8 Aug 2000
Yasui K, Kowa H, Nakaso K, Takeshima T, Nakashima K
Abstract excerpt
Plasma homocysteine and cysteine levels were measured in 90 patients with PD with the MTHFR C677T (T/T) genotype. The authors found that the levels of homocysteine-a possible risk factor for vascular disease-were elevated by 60% in levodopa-treated patients with PD, with the most marked elevation occurring in patients with the T/T genotype. Cysteine levels in subjects with PD did not differ from levels in control...
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