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Article

Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease.

Pharmacogenetics and genomics - 1 Oct 2012

Białecka Monika, Kurzawski Mateusz, Roszmann Anna, Robowski Piotr, Sitek Emilia J, Honczarenko Krystyna, Gorzkowska Agnieszka, Budrewicz Sławomir, Mak Monika, Jarosz Monika, Gołąb-Janowska Monika, Koziorowska-Gawron Ewa, Droździk Marek, Sławek Jarosław

Abstract excerpt

INTRODUCTION: Elevated plasma homocysteine (Hcy) concentration is an independent risk factor for cardiovascular disease, and its involvement in endothelial cell dysfunction is well established. However, the role of Hcy and folate in the pathogenesis of Parkinson's disease (PD) remains controversial. OBJECTIVES: The study was aimed at evaluating the relationships between Hcy, vitamin B12, and folic acid levels in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22890010
DOI: 10.1097/FPC.0b013e32835693f7

Genes

COMT
MTHFR

Provenance

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Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease.PMID 22890010Read ↗

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