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Article

Common single nucleotide polymorphism of hypoxia-inducible factor-1alpha and its impact on the clinicopathological features of esophageal squamous cell carcinoma.

Chinese journal of digestive diseases - 1 Jan 2005

Ling Ting Sheng, Shi Rui Hua, Zhang Guo Xin, Zhu Hong, Yu Lian Zhen, Ding Xia Feng

Abstract excerpt

OBJECTIVE: Angiogenesis is one of the most important molecular events in solid tumor development and growth, in which hypoxia-inducible factor (HIF)-1alpha is a key regulator and plays an important role. Studies have shown that a single nucleotide polymorphism (C1772T) in the HIF-1alpha gene exerts a large effect on the phenotype of human head and neck squamous cell carcinoma and renal cell carcinoma. But the...

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Share to Cancer, Hypoxia, and Metabolism
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Esophageal Neoplasms

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Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 16246222
DOI: 10.1111/j.1443-9573.2005.00223.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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