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Article

Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington's disease.

Behavioural brain research - 24 Aug 2009

Fowler Stephen C, Miller Benjamin R, Gaither Thomas W, Johnson Michael A, Rebec George V

Abstract excerpt

The R6/2 mouse is a popular model of Huntington's disease (HD) because of its rapid progression and measurable behavioral phenotype. Yet current behavioral phenotyping methods are usually univariate (e.g., latency to fall from a rotarod) and labor intensive. We used a force-plate actometer and sp...

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Identifiers

PMID: 19447289
DOI: 10.1016/j.bbr.2009.03.022
PMCID: PMC3711515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19447289-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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