Article
Subgrouping of patients with oral lichen planus according to cytochrome P450 enzyme phenotype and genotype.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Oct 2014
Kragelund C, Jensen S B, Hansen Cand Scient C, Broesen K, Torpet L A, Reibel J
Abstract excerpt
OBJECTIVE: This study aimed to determine if the activity of the environmentally influenced cytochrome P450 enzyme CYP1A2, alone or in combination with CYP2D6*4 genotype, discriminates subgroups of oral lichen planus (OLP) according to lifestyle factors and clinical manifestations. STUDY DESIGN: A total of 111 patients with OLP were categorized according to normal, low, or high CYP1A2 activity and CYP2D6 4...
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