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Article

The association between the COL12A1 gene and anterior cruciate ligament ruptures.

British journal of sports medicine - 1 Dec 2010

Posthumus Michael, September Alison V, O'Cuinneagain Dion, van der Merwe Willem, Schwellnus Martin P, Collins Malcolm

Abstract excerpt

BACKGROUND: Anterior cruciate ligament (ACL) ruptures are among the most severe musculoskeletal soft tissue injuries. However, the exact mechanisms which cause these acute injuries are unknown. Recently, sequence variants within two genes, namely COL1A1 and COL5A1, which code for the α1 chains of types I and V collagen respectively, were shown to be associated with ACL ruptures. Type XII collagen, similarly to...

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Identifiers

PMID: 19443461
DOI: 10.1136/bjsm.2009.060756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The association between the COL12A1 gene and anterior cruciate ligament ruptures.PMID 19443461Read ↗

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