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Article

The COL5A1 gene is associated with increased risk of anterior cruciate ligament ruptures in female participants.

The American journal of sports medicine - 1 Nov 2009

Posthumus Michael, September Alison V, O'Cuinneagain Dion, van der Merwe Willem, Schwellnus Martin P, Collins Malcolm

Abstract excerpt

BACKGROUND: Anterior cruciate ligament ruptures, especially to young female athletes, are a cause of major concern in the sports medicine fraternity. The major structural constituents of ligaments are collagens, specifically types I and V. Recently, the gene that encodes for the alpha1 chain of type I collagen (COL1A1) has been shown to be associated with an increased risk of cruciate ligament ruptures. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19654427
DOI: 10.1177/0363546509338266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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