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Article

Characterization of the Promoter Region of the Human c‐<i>kit</i> Proto‐oncogene

1 Nov 1993

Abstract excerpt

The c-kit proto-oncogene encodes a tyrosine kinase receptor for stem cell factor and plays a critical role in the growth and differentiation of various types of cells including hematopoietic stem cells. To investigate the mechanisms of its transcriptional regulation, we isolated the 5' flanking region of the human c-kit gene and characterized its promoter activity in hematopoietic cells. Nucleotide sequence...

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Identifiers

PMID: 7506248
DOI: 10.1111/j.1349-7006.1993.tb02813.x

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