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Article

Network analysis of differential expression for the identification of disease-causing genes.

PloS one - 1 Jan 2009

Nitsch Daniela, Tranchevent Léon-Charles, Thienpont Bernard, Thorrez Lieven, Van Esch Hilde, Devriendt Koenraad, Moreau Yves

Abstract excerpt

Genetic studies (in particular linkage and association studies) identify chromosomal regions involved in a disease or phenotype of interest, but those regions often contain many candidate genes, only a few of which can be followed-up for biological validation. Recently, computational methods to identify (prioritize) the most promising candidates within a region have been proposed, but they are usually not...

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Identifiers

PMID: 19436755
DOI: 10.1371/journal.pone.0005526
PMCID: PMC2677677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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