Article
Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplotype and pancreatic cancer in a high-risk cohort of smokers: a pilot study.
Pancreas - 1 Aug 2009
Fesinmeyer Megan Dann, Stanford Janet L, Brentnall Teresa A, Mandelson Margaret T, Farin Federico M, Srinouanprachanh Sengkeo, Afsharinejad Zahra, Goodman Gary E, Barnett Matt J, Austin Melissa A
Abstract excerpt
OBJECTIVES: The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PPARG) gene has been associated with diabetes and several cancers. This pilot study tested for the association between Pro12Ala and pancreatic cancer risk in a high-risk sample of smokers. METHODS: A nested case-control study was conducted in 83 incident cases of pancreatic cancer and 166 matched controls originally...
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