Article
Peroxisome proliferator-activated receptor-alpha (PPARA) genetic polymorphisms and breast cancer risk: a Long Island ancillary study.
Carcinogenesis - 1 Oct 2008
Golembesky Amanda K, Gammon Marilie D, North Kari E, Bensen Jeannette T, Schroeder Jane C, Teitelbaum Susan L, Neugut Alfred I, Santella Regina M
Abstract excerpt
Peroxisome proliferator-activated receptor-alpha (PPARA) has been shown to increase fatty acid oxidation and decrease cytokine levels and has been implicated in insulin production. Genetic variants of PPARA have been associated with cardiovascular disease, obesity and type II diabetes mellitus. Although no research to date has investigated the possible link between PPARA and breast cancer, the function of this...
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