Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

doi:10.1158/0008-5472.CAN-08-3441

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Article

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

Cancer research - 15 May 2009

Hennessy Bryan T, Gonzalez-Angulo Ana-Maria, Stemke-Hale Katherine, Gilcrease Michael Z, Krishnamurthy Savitri, Lee Ju-Seog, Fridlyand Jane, Sahin Aysegul, Agarwal Roshan, Joy Corwin, Liu Wenbin, Stivers David, Baggerly Keith, Carey Mark, Lluch Ana, Monteagudo Carlos, He Xiaping, Weigman Victor, Fan Cheng, Palazzo Juan, Hortobagyi Gabriel N, Nolden Laura K, Wang Nicholas J, Valero Vicente, Gray Joe W, Perou Charles M, Mills Gordon B

Abstract excerpt

Metaplastic breast cancers (MBC) are aggressive, chemoresistant tumors characterized by lineage plasticity. To advance understanding of their pathogenesis and relatedness to other breast cancer subtypes, 28 MBCs were compared with common breast cancers using comparative genomic hybridization, transcriptional profiling, and reverse-phase protein arrays and by sequencing for common breast cancer mutations. MBCs...

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PMID: 19435916
DOI: 10.1158/0008-5472.CAN-08-3441
PMCID: PMC2737191

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GATA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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