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Article

Heterocellular gene signatures reveal luminal-A breast cancer heterogeneity and differential therapeutic responses

2 Aug 2019

Abstract excerpt

Breast cancer is a highly heterogeneous disease. Although differences between intrinsic breast cancer subtypes have been well studied, heterogeneity within each subtype, especially luminal-A cancers, requires further interrogation to personalize disease management. Here, we applied well-characterized and cancer-associated heterocellular signatures representing stem, mesenchymal, stromal, immune, and epithelial...

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PMID: 31396557
DOI: 10.1038/s41523-019-0116-8

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