Geographic patterns of genome admixture in Latin American Mestizos.

doi:10.1371/journal.pgen.1000037

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Article

Geographic patterns of genome admixture in Latin American Mestizos.

PLoS genetics - 21 Mar 2008

Wang Sijia, Ray Nicolas, Rojas Winston, Parra Maria V, Bedoya Gabriel, Gallo Carla, Poletti Giovanni, Mazzotti Guido, Hill Kim, Hurtado Ana M, Camrena Beatriz, Nicolini Humberto, Klitz William, Barrantes Ramiro, Molina Julio A, Freimer Nelson B, Bortolini Maria Cátira, Salzano Francisco M, Petzl-Erler Maria L, Tsuneto Luiza T, Dipierri José E, Alfaro Emma L, Bailliet Graciela, Bianchi Nestor O, Llop Elena, Rothhammer Francisco, Excoffier Laurent, Ruiz-Linares Andrés

Abstract excerpt

The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. However, no genome-wide characterization of admixture across Latin America has yet been attempted. Here, we report an analysis of admixture in thirteen Mestizo populations (i.e. in regions of mainly European and Native settlement) from seven countries...

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PMID: 18369456
DOI: 10.1371/journal.pgen.1000037
PMCID: PMC2265669

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