Article
Detection of a mitochondrial kinase complex that mediates PKA-MEK-ERK-dependent phosphorylation of mitochondrial proteins involved in the regulation of steroid biosynthesis.
Methods in enzymology - 1 Jan 2009
Paz Cristina, Poderoso Cecilia, Maloberti Paula, Cornejo Maciel Fabiana, Mendez Carlos, Poderoso Juan J, Podestá Ernesto J
Abstract excerpt
In order to achieve the goal of this article, as an example we will describe the strategies followed to analyze the presence of the multi-kinase complex at the mitochondria and the posttranslational modification of two key mitochondrial proteins, which participate in the regulation of cholesterol transport across the mitochondrial membranes and in the regulation of steroid biosynthesis. Hormones, ions or growth...
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