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Article

Phosphorylation and function of the hamster adrenal steroidogenic acute regulatory protein (StAR).

The Journal of steroid biochemistry and molecular biology - 1 Aug 2004

Fleury Alain, Mathieu Axel P, Ducharme Lyne, Hales Dale Buchanan, LeHoux Jean-Guy

Abstract excerpt

In order to study the effect of phosphorylation on the function of the steroidogenic acute regulatory protein (StAR), 10 putative phosphorylation sites were mutated in the hamster StAR. In pcDNA3.1-StAR transfected COS-1 cells, decreases in basal activity were found for the mutants S55A, S185A and S194A. Substitution of S185 by D or E to mimic phosphorylation resulted in decreased activity for all mutants; we...

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Identifiers

PMID: 15336703
DOI: 10.1016/j.jsbmb.2004.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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