Article
A case-control study on the combined effects of p53 and p73 polymorphisms on head and neck cancer risk in an Italian population.
BMC cancer - 8 May 2009
Gallì Paola, Cadoni Gabriella, Volante Mariangela, De Feo Emma, Amore Rosarita, Giorgio Arianna, Arzani Dario, Paludetti Gaetano, Ricciardi Gualtiero, Boccia Stefania
Abstract excerpt
BACKGROUND: The purpose of this study is to analyze the combined effects of selected p53 and p73 polymorphisms and their interaction with lifestyle habits on squamous cell carcinoma of the head and neck (SCCHN) risk and progression in an Italian population. METHODS: Two hundred and eighty-three cases and 295 hospital controls were genotyped for p53 polymorphisms on exon 4 (Arg72Pro), intron 3 and 6, and p73...
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