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Genetic variants at 6p21.1 are associated with head and neck cancer in Chinese Han population.

Cancer biomarkers : section A of Disease markers - 1 Jan 2015

Wang Ruixia, Zhu Longbiao, Zhang Yu, Miao Limin, Ma Hongxia, Yuan Hua, Chen Ning

Abstract excerpt

BACKGROUND: A recent study synthesized several published genome-wide association studies (GWAS) on three types of cancers and identified variants at 6p21.1 and 7p15.3 as candidate susceptibility loci for multiple types of human cancers. However, the role of these loci in the development of head and neck cancer (HNC) is still unclear. METHODS: To evaluate the relationships between genetic variants in these regions...

Topics

Asian People
Carcinoma, Squamous Cell
Case-Control Studies
China
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 7
Female
Genetic Loci
Genetic Predisposition to Disease
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

Genotype

Head and Neck Neoplasms

Humans

Male

Middle Aged

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25524939
DOI: 10.3233/CBM-140442
PMCID: PMC12928511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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