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Article

Expression of human HtrA1, HtrA2, HtrA3 and TGF-β1 genes in primary endometrial cancer

6 May 2009

Abstract excerpt

The HtrA family of serine proteases takes part in cellular stress response including heat shock, inflammation and cancer. Downregulation of human HtrA1 and HtrA3 genes has been reported in some cancers, including endometrial cancer (EC), suggesting a tumor-suppressor role for both genes. The mechanism of the HtrA function is not known, however, evidence exists showing that both HtrA1 and HtrA3 regulate biological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19424634
DOI: 10.3892/or_00000385

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