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Serine Peptidase HTRA3 Is Closely Associated with Human Placental Development and Is Elevated in Pregnancy Serum1

26 Oct 2005

Abstract excerpt

HTRA3 is a newly identified serine peptidase of the mammalian HTRA (high-temperature requirement factor A) family, that is upregulated dramatically during mouse placental development. The current study determined whether HTRA3 was involved in human placentation. During the menstrual cycle, HTRA3 was expressed primarily in the endometrial glands, being significantly upregulated toward the mid- to late secretory...

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PMID: 16251496
DOI: 10.1095/biolreprod.105.047324

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Serine Peptidase HTRA3 Is Closely Associated with Human Placental Development and Is Elevated in Pregnancy Serum1PMID 16251496Read ↗

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HTRA1 in Placental Cell Models: A Possible Role in PreeclampsiaSemantic proximity Read ↗

Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2Semantic proximity Read ↗

Evolutionary conservation of mammalian HTRA3 and its developmental regulation in the rat ovary.Semantic proximity Read ↗

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Expression of human HtrA1, HtrA2, HtrA3 and TGF-β1 genes in primary endometrial cancerSemantic proximity Read ↗

Inhibition of HTRA3 stimulates trophoblast invasion during human placental developmentSemantic proximity Read ↗

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