Article
Decidual HtrA3 negatively regulates trophoblast invasion during human placentation.
Human reproduction (Oxford, England) - 1 Apr 2011
Singh Harmeet, Endo Yaeta, Nie Guiying
Abstract excerpt
BACKGROUND Controlled trophoblast invasion into the maternal decidua (interstitial invasion) is important for placental development. Factors secreted by the maternal decidual cells and the extravillous trophoblast can influence trophoblast invasion and abnormalities in the invasion process may lead to pregnancy complications. Serine protease HtrA3 is highly expressed in the decidual cells in the late secretory...
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