Article
Genetic variants in inflammation pathway genes and asthma in glioma susceptibility.
Neuro-oncology - 1 May 2010
Amirian E, Liu Yanhong, Scheurer Michael E, El-Zein Randa, Gilbert Mark R, Bondy Melissa L
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in inflammation-related genes have previously been shown to alter risks of developing various cancers. However, the effects of such SNPs on glioma risk remain unclear. We used a multistrategic approach to elucidate the relationship between glioma risk, asthma/allergies, and 23 literature-based functional SNPs in 11 inflammation genes. Genotyping was conducted on 373...
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