The CD3Z 844 T>A polymorphism within the 3'-UTR of CD3Z confers increased risk of incidence of systemic lupus erythematosus.

doi:10.1111/j.1399-0039.2009.01264.x

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Article

The CD3Z 844 T>A polymorphism within the 3'-UTR of CD3Z confers increased risk of incidence of systemic lupus erythematosus.

Tissue antigens - 1 Jul 2009

Warchoł T, Piotrowski P, Lianeri M, Cieślak D, Wudarski M, Hrycaj P, Lacki J K, Jagodziński P P

Abstract excerpt

Recently, a family-based association analysis showed that the haplotype carrying a low expression of the variant CD3Z 844 T>A (rs1052231) polymorphism located in the 3'-untranslated region of CD3Z predisposes to systemic lupus erythematosus (SLE) incidence. We analyzed the prevalence of the CD3Z 844 T>A polymorphism in SLE patients (n = 152) and controls (n = 304) in Poland. We observed that women with the CD3Z...

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PMID: 19422667
DOI: 10.1111/j.1399-0039.2009.01264.x

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