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Article

Association of CD14 genetic variants and circulating level with systemic lupus erythematosus risk in Egyptian children and adolescents.

Biomarkers in medicine - 1 Dec 2021

Attia Zeinab R, Zedan Mohamed M, Saad Entsar A, Mutawi Thuraya M, El Basuni Mohamed A

Abstract excerpt

Aim: To demonstrate whether sCD14 and CD14 (rs2569190 A/G and rs2569191 C/T) genetic variants are associated with systemic lupus erythematosus (SLE) risk, for the first time, in Egyptian pediatrics and adolescents. Materials & methods: sCD14 concentrations were determined in plasma of 95 SLE cases and 98 healthy controls using ELISA assay. Genotyping was performed using TaqMan technology. Results: sCD14 levels...

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PMID: 34743544
DOI: 10.2217/bmm-2021-0203

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