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The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites

1 Dec 1991

Abstract excerpt

An intragenic enhancer in the pol gene of human immunodeficiency virus type 1 has previously been identified (Verdin et al., Proc. Natl. Acad. Sci. USA 87:4874-4878, 1990). This element is composed of two subdomains both exhibiting phorbol ester-inducible enhancing activity on the viral thymidine kinase promoter in HeLa cells. Examination of the nucleotide sequence of one of these domains (nucleotides 4079 to...

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PMID: 1942259
DOI: 10.1128/jvi.65.12.7066-7072.1991

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