Article
Association of the aromatase gene alleles with BMD: epidemiological and functional evidence.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2009
Riancho José A, Sañudo Carolina, Valero Carmen, Pipaón Carlos, Olmos José M, Mijares Verónica, Fernández-Luna José L, Zarrabeitia María T
Abstract excerpt
BMD has a strong heritable component. Estrogen activity depends on the aromatization of androgenic precursors in nongonadal tissues both in postmenopausal women and men. Therefore, aromatase is an appealing candidate gene to explain, in part, the genetic component of BMD. In fact, an association...
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