Article
A gene-to-gene interaction between aromatase and estrogen receptors influences bone mineral density.
European journal of endocrinology - 1 Jul 2006
Riancho José A, Zarrabeitia María T, Valero Carmen, Sañudo Carolina, Mijares Verónica, González-Macías Jesús
Abstract excerpt
OBJECTIVE: The aromatization of androgenic precursors is the main source of estrogens in postmenopausal women. We tested the hypothesis that allelic variants of the genes coding for aromatase and estrogen receptors (ER) could interact to determine the estrogenic signals on the bone tissue and, co...
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