Article
[Molecular detection of the BCR-ABL gen by RT-PCR in Costa Rican children with leukemia].
Revista de biologia tropical - 1 Dec 2008
Jiménez-Arce Gerardo, Carrillo Juan, Chaves Mario, Jiménez Rafael, Vargas Mario, Campos Liliana, de la Guardia Ana, Valverde Berta
Abstract excerpt
Many leukemias could have chromosomic translocations and according to the transcripts formed by the genes involved, the patients present an specific phenotype of the leukemia. We show the first results of the investigation of the gen BCR-ABL using RT-PCR, in order to look for the t(9;22)(q34;q11) in pediatric leukemic children. We studied in total 55 patients, 6 (10.9%) of them were positive for that...
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