Article
[Polymorphism analysis of 5' promotor region of BCR gene].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jul 2004
Tian Hong, Zheng Wei-Yang, Fu Yong-Gui, Lin Jiang-Hai, Lu Feng-Juan, Zhou Shu-Yun
Abstract excerpt
BACKGROUND & OBJECTIVE: BCR-ABL fusion gene is regarded as the molecular hallmark of chronic myelogenous leukemia (CML), and its expression is controlled by the BCR gene promoter. This study was designed to investigate the polymorphism of the promoter region of BCR gene, and its possible correlation with the disease. METHODS: A 1.13 kb fragment of BCR gene 5' promotor region was amplified and sequenced from 30...
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