Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

Nature genetics - 1 Oct 2008

Barton Anne, Thomson Wendy, Ke Xiayi, Eyre Steve, Hinks Anne, Bowes John, Plant Darren, Gibbons Laura J, Wilson Anthony G, Bax Deborah E, Morgan Ann W, Emery Paul, Steer Sophia, Hocking Lynne, Reid David M, Wordsworth Paul, Harrison Pille, Worthington Jane

Abstract excerpt

The WTCCC study identified 49 SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-4) - 1 x 10(-5) (tier 3). Here we show that three of these SNPs, mapping to chromosome 10p15 (rs4750316), 12q13 (rs1678542) and 22q13 (rs3218253), are also associated (trend P = 4 x 10(-5), P = 4 x 1...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Case-Control Studies
Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 10
Share to Chromosomes, Human, Pair 12
Share to Chromosomes, Human, Pair 22
Share to Genetic Linkage
Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 18794857
DOI: 10.1038/ng.218
PMCID: PMC2662493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18794857-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.PMID 18794857Read ↗

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.Semantic proximity Read ↗

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.Semantic proximity Read ↗

Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.Semantic proximity Read ↗

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.Semantic proximity Read ↗

A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.Semantic proximity Read ↗

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.Semantic proximity Read ↗

A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.Semantic proximity Read ↗

Validation of the TAGAP rs212389 polymorphism in rheumatoid arthritis susceptibility.Semantic proximity Read ↗

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.Semantic proximity Read ↗

Rheumatoid arthritis association at 6q23.Semantic proximity Read ↗

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus.Semantic proximity Read ↗

Pathogenic variants screening in seventeen candidate genes on 2p15 for association with ankylosing spondylitis in a Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.