Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiae.

The Journal of biological chemistry - 19 Jun 2009

Lu Shu-Ping, Kato Michiko, Lin Su-Ju

Abstract excerpt

NAD(+) (nicotinamide adenine dinucleotide) is an essential cofactor involved in various biological processes including calorie restriction-mediated life span extension. Administration of nicotinamide riboside (NmR) has been shown to ameliorate deficiencies related to aberrant NAD(+) metabolism in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caloric Restriction
Share to N-Glycosyl Hydrolases
Share to Niacinamide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pentosyltransferases

Share to Pyridinium Compounds

Share to Silent Information Regulator Proteins, Saccharomyces cerevisiae

Share to Sirtuin 2

Share to Sirtuins

Source

Open in PubMed Open full text

Identifiers

PMID: 19416965
DOI: 10.1074/jbc.M109.004010
PMCID: PMC2719349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19416965-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiae.PMID 19416965Read ↗

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae.Semantic proximity Read ↗

Therapeutic potential of boosting NAD+ in aging and age-related diseasesSemantic proximity Read ↗

Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1.Semantic proximity Read ↗

Life span extension and neuronal cell protection by Drosophila nicotinamidase.Semantic proximity Read ↗

Sirtuin‐independent effects of nicotinamide on lifespan extension from calorie restriction in yeastSemantic proximity Read ↗

Yeast Life-Span Extension by Calorie Restriction Is Independent of NAD FluctuationSemantic proximity Read ↗

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.Semantic proximity Read ↗

A Genome-Wide Screen with Nicotinamide to Identify Sirtuin-Dependent Pathways in Saccharomyces cerevisiae.Semantic proximity Read ↗

Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and diseaseSemantic proximity Read ↗

Molecular Links between Caloric Restriction and Sir2/SIRT1 ActivationSemantic proximity Read ↗

The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.Semantic proximity Read ↗

Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.