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Article

Molecular Links between Caloric Restriction and Sir2/SIRT1 Activation

1 Jan 2014

Abstract excerpt

Ageing is the most significant risk factor for a range of prevalent diseases, including cancer, cardiovascular disease, and diabetes. Accordingly, interventions are needed for delaying or preventing disorders associated with the ageing process, i.e., promotion of healthy ageing. Calorie restriction is the only nongenetic and the most robust approach to slow the process of ageing in evolutionarily divergent...

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PMID: 25349818
DOI: 10.4093/dmj.2014.38.5.321

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