Article
Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia
1990-10-15
Abstract excerpt
Abstract Virtually all cases of childhood ALL have chromosomal abnormalities and half contain translocations, which are nearly equally divided between random and nonrandom rearrangements. Nonrandom chromosomal abnormalities have been correlated with leukemic cell lineage, the degree of cell differentiation, and the specific gene involved at the molecular level. Many cytogenetic findings have prognostic significanc...
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Identifiers and source
- Literature Corpus work
- 2b468425-eacf-59c7-9cf7-04e7642b35b7
- DOI
- 10.1182/blood.v76.8.1449.1449