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Article

Cre/lox recombination in the lower urinary tract

4 May 2009

Abstract excerpt

Tbx18 is a T-Box transcription factor that has specific expression and indispensible function in the lower urinary tract. Here, we report the generation and characterization of a bacterial artificial chromosome (BAC) transgene expressing Cre under the control of Tbx18 regulatory elements. When crossed to the ROSA26R-lacZ reporter mice, the Tbx18-Cre transgene mediates loxP recombination in the mesenchymal...

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PMID: 19415630
DOI: 10.1002/dvg.20515

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