Article
Emergence of quinolone-resistant Bordetella pertussis in Japan.
Antimicrobial agents and chemotherapy - 1 Jul 2009
Ohtsuka Masayuki, Kikuchi Ken, Shimizu Kenichiro, Takahashi Namiko, Ono Yuka, Sasaki Takashi, Hiramatsu Keiichi
Abstract excerpt
Six Bordetella pertussis strains isolated from children in Japan from 2004 to 2006 showed high-level resistance to nalidixic acid (NAL; MIC, >256 microg/ml) and decreased susceptibilities to fluoroquinolones. All of the NAL-resistant strains had the same D87G mutation in gyrA.
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