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Article

Emergence of Haemophilus influenzae with low susceptibility to quinolones isolated from pediatric patients in Japan.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Jul 2021

Takeuchi Noriko, Ohkusu Misako, Hoshino Tadashi, Yamamoto Shota, Segawa Shunsuke, Murata Shota, Ishiwada Naruhiko

Abstract excerpt

INTRODUCTION: In 2010, oral fluoroquinolone tosufloxacin (TFX) granules were released as the first oral respiratory quinolone for children in Japan. METHODS: To investigate the recent trend of H. influenzae strains with low susceptibility to quinolones in children, we analyzed the gene sequences of quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC, and parE of 23 clinical isolates from 15...

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PMID: 33658143
DOI: 10.1016/j.jiac.2021.02.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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