Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences.

Carcinogenesis - 1 Jul 2009

Timofeeva Maria N, Kropp Silke, Sauter Wiebke, Beckmann Lars, Rosenberger Albert, Illig Thomas, Jäger Birgit, Mittelstrass Kirstin, Dienemann Hendrik, Bartsch Helmut, Bickeböller Heike, Chang-Claude Jenny C, Risch Angela, Wichmann Heinz-Erich

Abstract excerpt

Cytochrome P450 (CYP) enzymes, involved in metabolism of tobacco carcinogens, are also involved in estrogen metabolism and many are regulated by estrogens. These genes may thus be of relevance to gender-specific differences in lung cancer risk, particularly in early-onset lung cancer, where a high proportion of women is observed. We conducted a case-control study to investigate genetic polymorphisms in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Lung Neoplasms

Share to Precancerous Conditions

Share to Risk Factors

Share to Sex Factors

Share to Smoking

Source

Identifiers

PMID: 19414505
DOI: 10.1093/carcin/bgp102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences.PMID 19414505Read ↗

The CYP3A4*1B allele increases risk for small cell lung cancer: effect of gender and smoking dose.Semantic proximity Read ↗

Association between CYP2A13 polymorphisms and lung cancer: A protocol for systematic review and meta-analysis.Semantic proximity Read ↗

Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.Semantic proximity Read ↗

CYP19A1 gene polymorphisms and risk of lung cancer.Semantic proximity Read ↗

Pulmonary CYP2A13 levels are associated with early occurrence of lung cancer-Its implication in mutagenesis of non-small cell lung carcinoma.Semantic proximity Read ↗

Missense variants in CYP4B1 associated with increased risk of lung cancer among Chinese Han population.Semantic proximity Read ↗

Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms.Semantic proximity Read ↗

CYP1A1 gene polymorphisms and smoking status as modifier factors for lung cancer risk.Semantic proximity Read ↗

Alcohol Consumption and Lung Cancer Risk in the Environment and Genetics in Lung Cancer Etiology (EAGLE) StudySemantic proximity Read ↗

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene.Semantic proximity Read ↗

Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases.Semantic proximity Read ↗

Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.