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Article

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

Atherosclerosis - 1 Jul 2013

Cox Amanda J, Ng Maggie C-Y, Xu Jianzhao, Langefeld Carl D, Koch Kenneth L, Dawson Paul A, Carr J Jeffrey, Freedman Barry I, Hsu Fang-Chi, Bowden Donald W

Abstract excerpt

OBJECTIVE: A negative relationship between total bilirubin concentration (TBili) and CVD risk has been documented in a series of epidemiological studies. In addition, TBili is thought to be under strong genetic regulation via the UGT1A gene family, suggesting it may be a heritable CVD risk factor. However, few studies directly relate TBili-associated UGT1A variants to CVD severity or outcome. This study...

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Source

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Identifiers

PMID: 23642732
DOI: 10.1016/j.atherosclerosis.2013.04.008
PMCID: PMC3691283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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