Article
HBx gene inducing hepatocellular carcinoma in vivo and its mechanism.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Apr 2009
Hou Zhouhua, Liu Guozhen, Zheng Fang, Tan Deming
Abstract excerpt
OBJECTIVE: To determine whether HBx gene can directly induce hepatocellular carcinoma in vivo, and to explore the mechanism of transplantation tumor in nude mice. METHODS: pCMVX/QSG7701 cell lines were vaccinated into subcutaneous tissue of nude mice. pRcCMV2/QSG7701 and QSG7701 cell lines were used as controls. The sections of transplantation tumor were observed microscopically by HE staining. RT-PCR was used to...
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