Article
Limited allelic diversity of stimulatory two-domain killer cell immunoglobulin-like receptors.
Human immunology - 1 Mar 2008
Hou Lihua, Steiner Noriko K, Chen Minghua, Belle Ian, Kubit Anna L, Ng Jennifer, Hurley Carolyn Katovich
Abstract excerpt
Genomic sequencing was used to characterize most of the coding regions of the five two-domain stimulatory killer cell immunoglobulin-like receptor (KIR) loci from 80 unrelated, primarily Caucasian, individuals. Specific loci were present in from 26% (KIR2DS3) to 98% (KIR2DS4) of individuals. The number of known alleles present varied from one (KIR2DS1, KIR2DS5) to five (KIR2DS4). The frequencies of loci and...
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